Usuku lweHlabathi lweSepsis: Ukwakha uMgca woKhuselo lwaKwangoko kwiSepsis ngeeReagents zokuHlola ngokuQondileyo

Minyaka le nge-13 kaSeptemba, ihlabathi libhiyozela uSuku lweHlabathi lweSepsis. Umxholo wehlabathi ka-2026 uthi “Tyala imali kwiSepsis – Gcina Ubomi,” ucela uluntu lwezonyango lwehlabathi ukuba lonyuse utyalo-mali ekuthinteleni nasekunyangweni kwe-sepsis. I-Sepsis kukungasebenzi kakuhle kwamalungu omzimba okusongela ubomi okubangelwa kukusabela okungalunganga kosulelo. E-China, izinga lokufa kwabantu abanesifo se-sepsis esibhedlele lisondela kwi-26%, kwaye izinga lokufa phakathi kwabaguli abakwi-ICU linokunyuka liye kwi-40%. Ukuchongwa kwangoko kunye nokuxilongwa ngokukhawuleza kubalulekile ekunciphiseni ukufa kwabantu abanesifo se-sepsis.

Nangona kunjalo, ukuxilongwa kwangoko kwe-sepsis kujongene nemingeni yokwenyani. Inkcubeko yegazi, njengomgangatho ophambili wokuxilongwa, inomjikelo omde wokukhula kunye nezinga eliphantsi lokuchuma, okwenza kube nzima ukubonelela ngobungqina obufanelekileyo bonyango lokuqala lokulwa nosulelo. Kwimeko enjalo, ii-reagents zokufumanisa uphawu lwe-serological ziye zaba zizixhobo zokuncedisa zokuxilonga kwizenzo zonyango, ngenxa yokulula kwazo, isantya, kunye nokukwazi ukubonelela ngeempawu zokuqala zesimo sosulelo ngovavanyo lwe-in vitro.

Njengomvelisi wee-reagents zokuxilonga ngezonyango, siyaqonda ngokupheleleyo ixabiso lesicwangciso see-reagents zokufumanisa i-sepsis kwiindlela zonyango. Okwangoku, iimpawu ezinxulumene ne-sepsis ezisetyenziswa rhoqo ziquka iiproteni zesigaba esibukhali ezifana nei-procalcitonin (PCT)kwaye Iprotheyini esebenzayo ye-C (CRP)kunye nee-cytokines ezivuthayo ezifanai-interleukin-6 (IL-6)Phakathi kwezi,I-PCTInyuka ngokukhawuleza ngexesha losulelo lwebhaktiriya oluqhelekileyo, kwaye izinga lokuphakama lihambelana nobunzima besifo; ukujonga okunamandla kunokukhokela nohlengahlengiso kunyango lwee-antibiotic. Kwiminyaka yakutshanje, iPresepsin, uphawu olutsha olubonisa ukusebenza kwe-monocyte/macrophage, itsale ingqalelo enkulu. Uxinzelelo lwayo kwi-plasma luyanda ngexesha losulelo lwebhaktiriya kwaye luyancipha emva konyango lwee-antibiotic, nto leyo enika umbono omtsha wokuxilongwa kwe-sepsis kwangoko.

Ngenxa yenkqubo enzima ye-pathophysiological ye-sepsis, uphawu olunye kunzima ukuhlangabezana nazo zonke iimfuno zeklinikhi. Ukufunyanwa okudibeneyo kweempawu ezininzi kunye novavanyo olunemilinganiselo emininzi olubandakanya iimodeli zokufunda koomatshini ziba zizikhokelo ezibalulekileyo zokuphucula ukuchaneka kokuxilongwa kwe-sepsis. Ukusuka kwiinzwa ze-optical ezisekwe kwi-nanomaterial ukuya kumaqonga e-microfluidic immunoassay, ukuphindaphinda kwetekhnoloji kwee-reagents zokufumanisa i-sepsis kuyakhawuleza.

NgeMini yeHlabathi yeSepsis, simema uluntu lwezonyango nolwezoshishino ukuba luqaphele kunye ukubaluleka kokubhaqwa kwe-sepsis kwangethuba. Ingxelo nganye echanekileyo evela kwi-reagent yokubhaqwa kwe-sepsis inokuqinisekisa ixesha lonyango olubalulekileyo kwisigulana.

I-Baysen Medical isoloko igxile kwindlela yokuxilonga ukuphucula umgangatho wobomi. Siphuhlise amaqonga etekhnoloji ama-5- iLatex, igolide ye-colloidal, uvavanyo lwe-Fluorescence Immunochromatographic, i-Molecular, i-Chemiluminescence Immunoassay, kunye ne-can yethu yokubonelelaUvavanyo lwe-CRP, Uvavanyo lwePCT, Uvavanyo lwe-CRP/SAA ,Uvavanyo lwe-IL-6,Uvavanyo lwe-IL-6/PCT comboNgeI-WIZ-A101kwayeI-WIZ-A203I-analzyer kulula ukuyisebenzisa kwaye ingafumana iziphumo zovavanyo kwimizuzu eli-15