Usuku Lomhlaba Wonke Lwe-Sepsis: Ukwakha Umugqa Wokuzivikela Wasekuqaleni Ku-Sepsis Ngezithasiselo Zokuxilonga Eziqondile

Njalo ngonyaka ngoSepthemba 13, umhlaba ugubha uSuku Lomhlaba Lwe-Sepsis. Isihloko somhlaba wonke sango-2026 sithi “Tshala Imali Ku-Sepsis – Londoloza Izimpilo,” sinxusa umphakathi wezokwelapha womhlaba wonke ukuthi wandise ukutshalwa kwezimali ekuvimbeleni nasekulapheni i-sepsis. I-Sepsis iwukungasebenzi kahle kwezitho zomzimba okusongela ukuphila okubangelwa ukusabela okungalawulwa kahle komnikazi ekuthelelekeni. E-China, izinga lokufa esibhedlela kweziguli ezine-sepsis lisondela ku-26%, kanti izinga lokufa phakathi kweziguli ezigulayo ezigulayo lingakhuphukela cishe ku-40%. Ukuhlonza kusenesikhathi kanye nokuxilongwa okusheshayo kubalulekile ekunciphiseni ukufa kwe-sepsis.

Kodwa-ke, ukuxilongwa kwe-sepsis kusenesikhathi kubhekene nezinselele zangempela. Ukuhlolwa kwegazi, njengendlela ejwayelekile yokuxilonga, kunomjikelezo omude wokuhlolwa kwegazi kanye nesilinganiso esiphansi sokutholakala kwezifo, okwenza kube nzima ukunikeza ubufakazi obufanele ngesikhathi sokwelashwa kokuqala kokwelashwa okulwa nokutheleleka. Ngokuphikisana nalokhu, ama-reagents okuthola izimpawu ze-serological abe ngamathuluzi okuhlola asizayo abalulekile emtholampilo, ngenxa yokulula kwawo, isivinini, kanye nekhono lokunikeza izinkomba zakuqala zesimo sokutheleleka ngokuhlolwa kwe-in vitro.

Njengomkhiqizi wezinto zokuxilonga zezokwelapha, siyaqonda ngokugcwele inani elibalulekile lezinto zokuxilonga ze-sepsis ezindleleni zezokwelapha. Njengamanje, izimpawu ezihlobene ne-sepsis ezisetshenziswa kakhulu zifaka amaprotheni esigaba esibukhali njengei-procalcitonin (PCT)futhi Iphrotheni e-C-reactive (CRP)kanye nama-cytokine avuvukalayo afanai-interleukin-6 (IL-6)Phakathi kwalezi,I-PCTIkhuphuka ngokushesha ngesikhathi sokutheleleka ngamagciwane emzimbeni, futhi izinga lokuphakama lihambisana nobunzima besifo; ukuqapha okunamandla kungaqondisa nokulungiswa kokwelashwa ngama-antibiotic. Eminyakeni yamuva nje, i-Presepsin, uphawu olusha olubonisa ukusebenza kwe-monocyte/macrophage, idonsele ukunaka kabanzi. Ukuhlushwa kwayo egazini kuyanda ngesikhathi sokutheleleka ngamagciwane futhi kwehla ngemva kokwelashwa ngama-antibiotic, okunikeza umbono omusha wokuxilongwa kwe-sepsis kwasekuqaleni.

Njengoba kunenqubo eyinkimbinkimbi ye-sepsis, kunzima ukuhlanekezela uphawu olulodwa. Ukutholwa okuhlanganisiwe kwezimpawu eziningi kanye nokuhlolwa okunezinhlangothi eziningi okuhlanganisa amamodeli okufunda komshini kuba yizinkomba ezibalulekile zokuthuthukisa ukunemba kokuxilonga kwe-sepsis. Kusukela kuzinzwa zokukhanya ezisekelwe ezintweni ezibonakalayo kuya kumapulatifomu e-microfluidic immunoassay, ukuphindaphinda kobuchwepheshe be-reagents yokuthola i-sepsis kuyashesha.

NgoSuku Lomhlaba Lwe-Sepsis, sinxusa imiphakathi yezokwelapha neyezimboni ukuthi iqaphele ngokubambisana ukubaluleka kokutholwa kwe-sepsis kusenesikhathi. Yonke imibiko enembile evela ku-reagent yokuthola i-sepsis ingaqinisekisa isikhathi sokwelashwa okubucayi kwesiguli.

I-Baysen Medical ihlala igxile ebuchwephesheni bokuxilonga ukuze ithuthukise ikhwalithi yempilo. Sithuthukise amapulatifomu obuchwepheshe ayi-5 - i-Latex, igolide le-colloidal, i-Fluorescence Immunochromatographic Assay, i-Molecular, i-Chemiluminescence Immunoassay, i-Our can supplyUkuhlolwa kwe-CRP, Ukuhlolwa kwe-PCT, Ukuhlolwa kwe-CRP/SAA ,Ukuhlolwa kwe-IL-6,Ukuhlolwa kwenhlanganisela ye-IL-6/PCTNgeI-WIZ-A101futhiI-WIZ-A203i-analzyer ilula ukuyisebenzisa futhi ingathola umphumela wokuhlolwa ngemizuzu eyi-15