Kuyini i-Gastrin?

I-Gastriniyi-hormone ekhiqizwa yisisu edlala indima ebalulekile ekulawuleni umgudu wokugaya ukudla. I-Gastrin ikhuthaza inqubo yokugaya ukudla ngokuyinhloko ngokuvuselela amaseli e-mucosal esiswini ukuthi akhiphe i-asidi yesisu kanye ne-pepsin. Ngaphezu kwalokho, i-gastrin ingakhuthaza futhi i-peristalsis yamathumbu, yandise ukujikeleza kwegazi kwesisu, futhi ikhuthaze ukulungiswa nokuvuselelwa kwe-mucosa yamathumbu. Ukukhiqizwa kwe-gastrin kuthonywa ukudla, ukuguqulwa kwe-neuro, kanye namanye ama-hormone.

Ukubaluleka kokuhlolwa kwe-Gastrin

I-Gastrin ibaluleke kakhulu ekuhlolweni kwezifo zesisu. Ngenxa yokuthi ukukhishwa kwe-gastrin kuthinteka ukudla, ukuguqulwa kwemizwa, kanye namanye ama-hormone, amazinga e-gastrin angalinganiswa ukuhlola isimo sokusebenza kwesisu. Isibonelo, uma ukukhishwa kwe-asidi yesisu okunganele noma i-asidi yesisu eningi kakhulu, amazinga e-gastrin angatholakala ukusiza ekuxilongweni nasekuhlolweni kwezifo ezihlobene ne-asidi yesisu, njengezilonda zesisu, isifo se-gastroesophageal reflux, njll.

Ngaphezu kwalokho, ukukhiqizwa okungajwayelekile kwe-gastrin kungase kuhlotshaniswe nezinye izifo zesisu, njengezimila ze-neuroendocrine zesisu. Ngakho-ke, ekuhlolweni nasekuxilongweni kwezifo zesisu, ukuhlanganisa ukutholakala kwamazinga e-gastrin kunganikeza ulwazi olusizayo oluthile futhi kusize odokotela benze ukuhlolwa okuphelele kanye nokuxilongwa. Kodwa-ke, kufanele kuphawulwe ukuthi ukutholakala kwamazinga e-gastrin ngokuvamile kudinga ukuhlanganiswa nezinye izivivinyo zemitholampilo kanye nokuhlaziywa okuphelele kwezimpawu futhi akukwazi ukusetshenziswa njengesisekelo sokuxilongwa kuphela.

Lapha sigxile kakhulu kwezokwelapha eBaysen ezindleleni zokuxilonga ukuze sithuthukise ikhwalithi yempilo,Ikhithi yokuhlola i-Cal , Ikhithi yokuhlola ye-Gastrin -17 , Ukuhlolwa kwe-PGI/PGII, Futhi nginayoIkhithi yokuhlola ye-Gastrin 17/PGI/PGIIukuthola izifo zesisu