WHAKARĀPOPOTONGA

Hei pūmua wāhanga whakapeka, nō roto te amyloid A toto i ngā pūmua rerekē o te whānau apolipoprotein, e
he taumaha ngota whanaunga tata ki te 12000. He maha ngā cytokine e whai wāhi ana ki te whakahaere i te whakaaturanga SAA
i roto i te urupare wāhanga whakapeka. Ka whakaohokia e te interleukin-1 (IL-1), te interleukin-6 (IL-6) me te tumor necrosis factor-α
(TNF-α), ka hangaia te SAA e ngā macrophages kua whakahohehia me te fibroblast i roto i te ate, he poto noa te haurua-ora o
tata ki te 50 meneti. Ka tere te hono a te SAA ki te lipoprotein kiato-teitei (HDL) i roto i te toto i te hanganga i roto i te ate, e
me whakahoro e te toto, te mata o te pūtau me ngā protease ā-roto. Mēnā he mate pāwera, he mate mau tonu rānei
mumura, mate pāwera rānei, ka puhoi haere te tere o te pirau o te SAA i roto i te tinana, i te mea ka piki haere te hanga,
e hua ake ai te pikinga tonu o te kukū SAA i roto i te toto. He pūmua wāhanga whakapeka te SAA, ā, he mumura hoki
tohu i hangaia e ngā pūtau ate. Ka piki ake te kukū o te SAA i roto i te toto i roto i ngā haora e rua i muri i te
te puta o te mumura, ā, ka piki ake te kukū o te SAA ki te 1000 ngā wā i te wā o te mumura whakapeka
mumura. Nō reira, ka taea te whakamahi i te SAA hei tohu mō te mate moroiti, ngā momo mumura rānei, e
ka āwhina i te tautuhi i te mumura me te aroturuki i ngā mahi rongoā.

Ka taea te whakamahi i tā mātou Kete Tātaritanga mō te Amyloid A i roto i te toto (Fluorescence Immunochromatographic Assay) hei kimi i te paturopi ki te amyloid A i roto i te toto (SAA) i roto i te tauira toto tangata/plasma/toto katoa, ā, ka whakamahia hei tātaritanga āwhina mō te mumura, te mate pāwera rānei, te mate kino rānei, me te mate pūmau, te mate kino rānei.

Nau mai ki te whakapā mai mō ētahi atu kōrero mēnā he hiahia tōu.