Gupima neza, Kurinda Ubuzima bw'Igifu: Ibisubizo byo Gupima H. ​​pylori mu buryo bumwe

Helicobacter pylori (H. pylori)Ishyirahamwe ry’Umuryango w’Abibumbye ryita ku Buzima mu cyiciro cya mbere cy’indwara ya kanseri mu mubiri, kandi ni ikintu gikomeye gitera indwara ya gastritis idakira, ibisebe byo mu gifu, ndetse na kanseri yo mu gifu. Bitewe n’uko umubare munini w’abandura ugaragara mu turere twinshi, gusuzuma hakiri kare no gusuzuma neza ni ingenzi mu gukumira no gucunga indwara zo mu gifu. Nk’ikigo cy’inzobere mu gusuzuma indwara, dutanga urutonde rw’ibizamini by’indwara imwe gusa—kuva ku isuzuma rya mbere kugeza ku gupima neza—kugira ngo duhuze n’ibikenewe mu buvuzi no mu gusuzuma.

Gusuzuma neza: Gupima umwuka n'ibikoresho byihuse

Ku bijyanye no kwipimisha ubuzima ku rwego runini no gupimwa abarwayi bataha, C13/C14Ikizamini cy'ubuhumekero bwa UreaIzwi ku rwego mpuzamahanga nk'igipimo cya zahabu cyo gupima H. ​​pylori, itanga isuzuma ritavangiye kandi rifite ubuziranenge burenga 95%. Isotope ya C13 ntabwo ikoresha imirasire kandi ikwiriye abantu bose, harimo abagore batwite n'abana, mu gihe isuzuma rya C14 ritanga ubundi buryo buhendutse kandi bunoze.

Mu buryo bunyuranye, dutanga uburyo bworoshye bwoHP-AB (antibody)naIbikoresho byo gupima byihuse bya HP-AG (antigen).IcyoHP-ABikizamini gipima abasirikare b’umubiri hakoreshejwe amaraso cyangwa serumu yo mu rutoki, bigatanga ibisubizo mu minota 15—ni byiza cyane mu bushakashatsi ku ndwara.Ikizamini cya HP-AGIpima antigens mu myenge, igaragaza neza uko indwara ihagaze. Ikora nk'inyongera ku isuzuma ry'umwuka, cyane cyane ku bantu bihariye aho ubundi buryo bwo gupima bushobora kugorana.

Isuzuma ry'ibizamini: Ikoranabuhanga rya Fluorescence Immunoassay

Kugira ngo duhuze icyifuzo cy’ubuvuzi cyo gukurikirana indwara no gusuzuma umusaruro w’ubuvuzi, twashyizeho ibikoresho bipima HP-AG na HP-AB bikoreshwa naWIZ-101naWIZ-A203urubuga. Ubu buryo bukoresha fluorescence immunochromatography ishingiye ku gihe, ihuza antibody zihariye na microspheres fluorescent. Bitandukanye n'udupira tw'ibizamini bisanzwe, ubu buryo butuma habaho gupima neza ingano y'antibody/antigen. Ibi ntibifasha abaganga gusa gusuzuma ubukana bw'ubwandu ahubwo binatuma habaho isuzuma nyaryo ry'ibyavuye mu buvuzi bwo kurandura indwara, bigatanga amakuru yizewe yo gufata ibyemezo byo kwa muganga.

Kuva ku gupima umwuka hifashishijwe spectrometry kugeza kuri immunochromatography, no kuva ku gupima neza kugeza ku gupima hakoreshejwe fluorescence, twiyemeje gutanga urutonde rw'ibicuruzwa bifasha ibigo by'ubuvuzi kugera ku buryo bwo kwirinda no kugenzura ubwandu bwa H. pylori mu gifu.