Kuona Nekunyatsojeka, Kudzivirira Hutano Hwedumbu: Mhinduro Dzekuyedza H. pylori Dzoga

Helicobacter pylori (H. pylori)Inorongwa neWorld Health Organisation seboka reboka rekutanga rekenza yemudumbu uye chinhu chikuru chinokonzera gastritis isingaperi, maronda emudumbu, uye kunyange kenza yemudumbu. Zvichienderana nehuwandu hwakanyanya hwehutachiona munzvimbo dzakawanda, kuongororwa kwekutanga uye kuongororwa kwakarurama kwakakosha pakudzivirira nekutarisira zvirwere zvemudumbu. Sekambani yehunyanzvi yekuongorora zvirwere, tinopa portfolio yakazara yekuongorora kamwe chete—kubva pakuongorora kwekutanga kusvika pakuyera kwakarurama—kuti tisangane nezvinodiwa zvakasiyana-siyana zvekiriniki nekuongorora.

Kuongorora Zvinoshanda: Kuedza Kufema uye Kukurumidza Kugadzirisa Matambudziko

Pakuongororwa kwehutano kwakakura uye kuongororwa kwevarwere vasiri muchipatara, C13/C14Kuedzwa kweUrea Breathinozivikanwa pasi rose senzira yepamusoro yekuongorora H. pylori, ichipa bvunzo dzisingapindike uye dzakarurama kupfuura 95%. Iyo C13 isotope haina radioactive uye yakakodzera vanhu vese, kusanganisira vakadzi vane pamuviri nevana, nepo bvunzo yeC14 ichipa imwe nzira inodhura uye inoshanda.

Panguva imwe chete, tinopa zviri nyoreHP-AB (antibody)uyeKits dzekuyedza nekukurumidza dzeHP-AG (antigen). IyoHP-ABbvunzo iyi inoona masoja ekudzivirira chirwere achishandisa ropa kana seramu yemunwe, zvichipa mhinduro mukati memaminitsi gumi nemashanu—yakanakira kuongororwa kwezvirwere.Kuedzwa kweHP-AGInoona maantigen ari mutsvina, ichiratidza zvakananga mamiriro ehutachiona. Inoshanda sechibatsiro chinoshanda pabvunzo yekufema, kunyanya inobatsira kune vanhu vakasiyana uko kumwe kuyedza kunogona kuoma.

Kuyera Kwakarurama: Tekinoroji yeFluorescence Immunoassay

Kuti tikwanise kusangana nezvinodiwa zvekiriniki zvekutarisa chirwere uye kuongorora kushanda kwemishonga, takaunza ma reagents ehuwandu hweHP-AG neHP-AB anoshandiswa neWIZ-101uyeWIZ-A203mapuratifomu. Sisitimu iyi inoshandisa fluorescence immunochromatography yakagadziriswa nenguva, ichibatanidza ma antibodies chaiwo nema microspheres e fluorescent. Kusiyana nemitsetse yekuedza yemhando yepamusoro yechinyakare, tekinoroji iyi inogonesa kuyera kwakanyatsojeka kwehuwandu hwema antibody/antigen. Izvi hazvingobatsiri vanachiremba chete pakuongorora kuoma kwehutachiona asiwo zvinogonesa kuongororwa kwakarurama kwemhedzisiro yekurapa, zvichipa ruzivo rwakavimbika rwekuita sarudzo dzekiriniki.

Kubva pakuyedzwa kwekufema kwakavakirwa pa mass spectrometry kusvika pa immunochromatography, uye kubva pakuongororwa kwemhando yepamusoro kusvika pakuyerwa kwe fluorescence, takazvipira kupa huwandu hwakakwana hwezvigadzirwa zvinopa simba kumasangano ehutano kuti akwanise kudzivirira nekudzora hutachiona hweH. pylori mudumbu.