H. pyloriI-WHO ihlelwe njenge-Group I biological carcinogen kwaye yeyona nto iphambili ebangela isifo se-gastritis esingapheliyo, izilonda ze-peptic, kwanomhlaza wesisu. Ngenxa yesantya esiphezulu sosulelo kwiindawo ezininzi, ukuxilongwa kwangethuba kunye nokuxilongwa ngokuchanekileyo kubalulekile ekuthinteleni nasekulawuleni izifo zesisu. Njengenkampani yobuchwephesha yokuxilongwa kwezonyango, sinikezela ngepotifoliyo epheleleyo yovavanyo olupheleleyo—ukusuka ekuhlolweni kokuqala ukuya ekulinganisweni ngokuchanekileyo—ukuze sihlangabezane neemfuno ezahlukeneyo zeklinikhi kunye nokuhlolwa.

Uvavanyo Olusebenzayo: Isihlalutyi sokuphefumla se-Urea se-C13 kunye ne-C14kunye nekhithi yovavanyo

Ukuhlolwa kwempilo enkulu kunye nokuhlolwa kwezigulane ezingalaliswanga,C13/C14 Urea Breath Uvavanyo luqatshelwa kwihlabathi liphela njengomgangatho wegolide wokufumanisa i-H. pylori, lubonelela ngovavanyo olungangenisi ntsholongwane oluchanekileyo oludlula i-95%. I-isotope ye-C13 ayisebenzisi imitha kwaye ifanelekile kubo bonke abantu, kuquka abafazi abakhulelweyo nabantwana, ngelixatuvavanyo lwe-C14ibonelela ngenye indlela engabizi kakhulu nesebenzayo.

Ngaxeshanye, sinikeza uncedo olululaI-HP-AB (i-antibody) kwayeI-HP-AG (i-antigen) Iikiti zovavanyo ezikhawulezayo. Uvavanyo lwe-HP-AB lufumanisa ii-antibodies ngokusebenzisa igazi okanye i-serum esecaleni komunwe, lunika iziphumo kwimizuzu eli-15—lulungele uphando lwe-epidemiological. Uvavanyo lwe-HP-AG lufumanisa ii-antigens kwiisampuli zendle, olubonisa ngokuthe ngqo imeko yosulelo olusebenzayo. Lusebenza njengesincedisi esisebenzayo kuvavanyo lokuphefumla, ngakumbi kumaqela athile apho olunye uvavanyo lunokuba nzima.

Ubungakanani obuchanekileyo: Itekhnoloji ye-Fluorescence Immunoassay

Ukuze sihlangabezane neemfuno zonyango zokujonga izifo kunye novavanyo lokusebenza kakuhle konyango, siye sazisa ubungakananiI-HP-AGkwayeIi-reagents ze-HP-ABixhaswa yiI-WIZ-101kwayeI-WIZ-A203amaqonga. Le nkqubo isebenzisa i-immunochromatography ye-fluorescence exazululwe ngexesha, idibanisa ii-antibodies ezithile kunye nee-microspheres ze-fluorescent. Ngokungafaniyo nemicu yovavanyo olusemgangathweni yendabuko, le teknoloji ivumela ukulinganiswa okuchanekileyo kobuninzi be-antibody/antigen concentrations. Oku akuncedi nje kuphela oogqirha ekuvavanyeni ubunzima bosulelo kodwa kukwavumela uvavanyo oluchanekileyo lweziphumo zonyango lokuphelisa, inika idatha ethembekileyo ngakumbi yokwenza izigqibo zeklinikhi.

Ukususela kuvavanyo lokuphefumula olusekelwe kwi-mass spectrometry ukuya kwi-immunochromatography, ukusuka kuvavanyo lomgangatho ukuya kuvavanyo olusekelwe kwi-fluorescence, sizimisele ukubonelela ngepotifoliyo yemveliso ebanzi enika amandla amaziko ezempilo ukuba afezekise uthintelo oluchanekileyo kunye nolawulo lwesisu.H. pyloriusulelo.