(I-ASEAN, i-Association of Southeast Asian Nations, kunye neMalaysia, i-Indonesia, iThailand, iiPhilippines, iSingapore, iBrunei, iVietnam, iLaos, iMyanmar kunye neCambodia, yeyona ngongoma iphambili kwingxelo yesivumelwano saseBangkok ekhutshwe kunyaka ophelileyo, okanye inokubonelela ngonyango losulelo lweHelicobacter pylori. Ezinye izimvo.)

Usulelo lweHelicobacter pylori (Hp) luhlala lutshintsha, kwaye iingcali kwicandelo lokugaya ukutya bezicinga ngecebo elifanelekileyo lokunyanga. Unyango losulelo lweHp kumazwe ase-ASEAN: INgqungquthela yeSivumelwano saseBangkok ihlanganise iqela leengcali eziphambili ezivela kulo mmandla ukuze zihlolisise kwaye zivavanye usulelo lweHp ngokwemigaqo yezonyango, kwaye ziphuhlise iingxelo zemvumelwano, iingcebiso, kunye neengcebiso zonyango lweklinikhi losulelo lweHp kumazwe ase-ASEAN. INgqungquthela yeSivumelwano sase-ASEAN ibizinyaswe ziingcali zamazwe ngamazwe ezingama-34 ezivela kumazwe ali-10 angamalungu e-ASEAN kunye neJapan, iTaiwan kunye ne-United States.

Intlanganiso igxile kwizihloko ezine:

(I) unxibelelwano lwe-epidemiology kunye nezifo;

(II) iindlela zokuxilonga;

(III) izimvo zonyango;

(IV) ukulandelwa emva kokupheliswa.

Ingxelo yemvumelwano

Ingxelo 1:1a: Ukosuleleka yi-Hp kwandisa umngcipheko weempawu ze-dyspeptic. (Inqanaba loBungqina: Phezulu; Inqanaba eliCetywayo: Akukho); 1b: Zonke izigulana ezine-dyspepsia kufuneka zivavanywe kwaye zinyangwe ukosuleleka yi-Hp. (Inqanaba lobungqina: Phezulu; inqanaba eliCetywayo: strong)

Ingxelo 2:Ngenxa yokuba ukusetyenziswa kwe-Hp infection kunye/okanye amayeza angengo-steroidal anti-inflammatory (NSAIDs) kunxulumene kakhulu ne-peptic ulcers, unyango oluphambili lwe-peptic ulcers kukuphelisa i-Hp kunye/okanye ukuyeka ukusebenzisa ii-NSAIDs. (Inqanaba lobungqina: eliphezulu; inqanaba elicetyiswayo: elinamandla)

Ingxelo 3:Ukwanda komhlaza wesisu ngokweminyaka kumazwe ase-ASEAN yi-3.0 ukuya kwi-23.7 kwi-100,000 yabantu ngonyaka. Kumazwe amaninzi ase-ASEAN, umhlaza wesisu usengomnye wezona zizathu ziphambili ezili-10 zokufa komhlaza. I-gastric mucosa-associated lymphoid tissue lymphoma (stomach MALT lymphoma) ayifumaneki lula. (Inqanaba lobungqina: liphezulu; inqanaba elicetyiswayo: Akukho)

Ingxelo 4:Ukususwa kwe-Hp kunokunciphisa umngcipheko womhlaza wesisu, kwaye amalungu osapho lwezigulane ezinomhlaza wesisu kufuneka ahlolwe aze anyangwe i-Hp. (Inqanaba lobungqina: eliphezulu; inqanaba elicetyiswayo: eliqinileyo)

Ingxelo 5:Izigulane ezine-gastric MALT lymphoma kufuneka zisuswe ngenxa ye-Hp. (Inqanaba lobungqina: eliphezulu; inqanaba elicetyiswayo: elinamandla) 

Ingxelo 6:6a: Ngokusekelwe kumthwalo wentlalo wesifo, kubiza kancinci ukwenza uvavanyo loluntu lwe-HP ngovavanyo olungangenisi gazi ukuthintela ukupheliswa komhlaza wesisu. (Inqanaba lobungqina: liphezulu; inqanaba elicetyiswayo: libuthathaka)

6b: Okwangoku, kumazwe amaninzi ase-ASEAN, ukuvavanywa komhlaza wesisu woluntu nge-endoscopy akunakwenzeka. (Inqanaba loBungqina: Phakathi; Inqanaba elicetyiswayo: Elibuthathaka)

Ingxelo 7:Kumazwe ase-ASEAN, iziphumo ezahlukeneyo zosulelo lwe-Hp zimiselwa kukunxibelelana phakathi kwezinto ezibangela ubungozi be-Hp, izinto ezibangela umnini kunye nezinto ezisingqongileyo. (Inqanaba lobungqina: eliphezulu; inqanaba elicetyiswayo: Akukho)

Ingxelo 8:Zonke izigulane ezinezilonda zomhlaza wesisu ngaphambi kokuba umhlaza uqalise umhlaza kufuneka zifumane unyango lwe-Hp, kwaye zihlukanise umngcipheko womhlaza wesisu ngokwezigaba. (Inqanaba lobungqina: liphezulu; umlinganiselo ocetyiswayo: uqinile)

Indlela yokuxilonga i-Hp

Ingxelo 9:Iindlela zokuxilonga i-Hp kummandla we-ASEAN ziquka: uvavanyo lokuphefumula kwe-urea, uvavanyo lwe-fecal antigen (i-monoclonal) kunye novavanyo lwe-requisited urease test (RUT)/histology oluqinisekisiweyo localized. Ukukhetha indlela yokufumanisa kuxhomekeke kukhetho lwesigulana, ukufumaneka kwaso, kunye neendleko zaso. (Inqanaba lobungqina: eliphezulu; inqanaba elicetyiswayo: eliqinileyo) 

Ingxelo 10:Ukufunyanwa kwe-Hp okusekelwe kwi-biopsy kufuneka kwenziwe kwizigulana ezithatha i-gastoscopy. (Inqanaba loBungqina: Phakathi; Inqanaba elicetyiswayo: Eliqinileyo)

Ingxelo 11:Ukufunyanwa kwe-Hp proton pump inhibitor (PPI) kuyekiswa ubuncinane iiveki ezi-2; amayeza okubulala iintsholongwane ayekiswa ubuncinane iiveki ezi-4. (Inqanaba lobungqina: liphezulu; umlinganiselo ocetyiswayo: unamandla)

Ingxelo 12:Xa kufuneka unyango lwe-PPI oluhlala ixesha elide, kuyacetyiswa ukuba kubonwe i-Hp kwizigulana ezinesifo se-gastroesophageal reflux (GERD). (Inqanaba loBungqina: Phakathi; Uvavanyo oluCetyisiweyo: Oluqinileyo)

Ingxelo 13:Izigulana ezifuna unyango lwexesha elide ngee-NSAIDs kufuneka zivavanywe kwaye zinyangwe i-Hp. (Inqanaba lobungqina: liphezulu; inqanaba elicetyiswayo: liqinile) 

Ingxelo 14:Kwizigulane ezine-peptic ulcer ophayo kunye ne-negative Hp initial biopsy, usulelo kufuneka luqinisekiswe kwakhona ngovavanyo lwe-Hp olulandelayo. (Inqanaba loBungqina: Phakathi; Inqanaba elicetyiswayo: Eliqinileyo)

Ingxelo 15:Uvavanyo lokuphefumula lwe-urea lolona khetho lufanelekileyo emva kokususwa kwe-Hp, kwaye uvavanyo lwe-antigen yendle lungasetyenziswa njengenye indlela. Uvavanyo kufuneka lwenziwe ubuncinane kwiiveki ezi-4 emva kokuphela konyango lokuphelisa. Ukuba kusetyenziswa i-gastroscope, i-biopsy inokwenziwa. (Inqanaba lobungqina: eliphezulu; inqanaba elicetyiswayo: eliqinileyo)

Ingxelo 16:Kucetyiswa ukuba amagunya ezempilo kazwelonke kumazwe ase-ASEAN abuyisele i-HP ngovavanyo kunye nonyango lokuxilonga. (Inqanaba lobungqina: liphantsi; inqanaba elicetyiswayo: liqinile)