Urhudo olungapheliyo oluhlala iiveki ezingaphezu kwezine luphawu "lwesilumkiso esibomvu" oluvakala emathunjini, kwaye kufuneka uqaphele isifo samathumbu esidumbileyo (IBD).

Kodwa nantsi ingxaki: xa ungena ekliniki, ugqirha ufumanisa njani ukuba amathumbu akho avuvukile ngokwenene? ​​Kwaye ukuba ukuvuvuka kukhulu kangakanani? Okwangoku, uvavanyo olubonakala “lungaqhelekanga” luqala ukusebenza —i-calprotectin yendle uvavanyo. Kufana “nomtoliki” othembekileyo onokuguqulela “ukuhleba” kwamathumbu abe yidatha enokuqondakala ngoogqirha. Kule ncwadana ethi “Uyazi Kangakanani Ngamathumbu,” siza kukunceda ukuba umazi lo “mtoliki” wempilo yamathumbu.

1) Xa amathumbu evuvukile, ngubani onokusixelela?

Khawucinge nje: amathumbu akho “avutha ngumlilo,” kodwa awukwazi ukuwabona okanye ukuwachukumisa — unokuqikelela kuphela “ngemiqondiso engathanga ngqo” efana norhudo kunye nentlungu yesisu.

Ngaba ikho indlela enokusixelela ngokuthe ngqo nangokungakhethi cala — ukuba amathumbu avuvukile kwaphela na? Kwaye ukuba ukuvuvuka kukhulu kangakanani?

Impendulo ithi: ewe. Kwaye ifihlwe kanye esitulweni sakho.

Xa kuvela ukudumba kwamathumbu, ii-neutrophils ziqokelelana ngamanani amakhulu kwindawo yokudumba ukuze “zicime umlilo.” Ngexesha “lo mlo,” ezi seli zikhupha iproteni —i-calprotectinIkhutshwa emzimbeni kunye nendle, kwaye ukugxila kwayo kubonisa ngokuthe ngqo ubukhali bokuvuvukala kwamathumbu.

2)I-Calprotectin: Kutheni le nto itsale ingqalelo yezonyango?

Ngaphambii-calprotectinkwavela, oogqirha baxhomekeke kakhulu kwiimpawu zegazi (ezifanaI-CRP, ESR, njl.njl.) ukugweba ukudumba. Kodwa ezi mpawu "zinesiphako esibulalayo" - azinazo iinkcukacha ezithile zamathumbu. Ngamanye amazwi, ukuba ziphezulu, zinokubonisa ukudumba ndaweni ithile emzimbeni, kodwa kungekhona emathunjini.I-Calprotectinyahlukile. Ineenzuzo ezininzi zendalo:

Inyani enye:i-calprotectin yendle ifakiwe kwizikhokelo zaseTshayina zokuxilonga nokunyanga isifo samathumbu esidumbileyo, ibe yi-biomarker esetyenziswa rhoqo kwizonyango.

3) Yintoni le "toliki" ingasinceda siyenze?

Izicelo zonyango zei-calprotectin yendle ziya zisanda ngakumbi, ikakhulu kuquka ezi nkalo zilandelayo:

① Ukwahlula i-IBD kwi-IBS

Le yeyona "ikhethekileyo" ye-calprotectin. Iimpawu ze-irritable bowel syndrome (IBS) kunye nesifo samathumbu esivuthayo (IBD) ngamanye amaxesha zinokufana kakhulu - zombini zinokubangela iintlungu zesisu, urhudo, kunye notshintsho kwimikhwa yamathumbu. Kodwa ezi zimbini zahlukile ngokupheleleyo: I-IBS sisifo esisebenzayo, esingenalo ukuvuvukala okungokwemvelo emathunjini; IBD kukuvuvukala kwamathumbu okwenyani.

② Ukuvavanya umsebenzi wesifo

Kwizigulane esele zifunyaniswe zine-IBD,i-calprotectinNgaba unokuxelela oogqirha: ingaba esi sifo sikwinqanaba elisebenzayo okanye sisekuxolelweni? Izifundo zibonisa ukuba amanqanaba e-calprotectin yendle anxulumene kakhulu nomlinganiselo wokudumba kwamathumbu okubonwa phantsi kwe-endoscopy. Okukhona ixabiso liphezulu, kokukhona ukudumba kusiba nzima; ukwehla kwexabiso kunokusebenza njengenye yezalathisi zogqirha zokuvavanya ukusebenza kakuhle konyango.

③ Ukubeka esweni ukusebenza kakuhle kunye nokuqikelela ukuphinda ubuye

I-IBD sisifo esingapheliyo esifuna unyango oluhlala ixesha elide.I-Calprotectinkufana “nomlindi.” Ukwehla kwe-calprotectin emva konyango kunokubonisa ukuba unyango luyasebenza; ukuba i-calprotectin iqala ukunyuka kwisigulana xa siphumla, inokubonisa ukuphinda sibuyele esiqhelweni, okuvumela oogqirha ukuba balungise isicwangciso sonyango kwangaphambili.

④ Ukuphanda unobangela wokungakhululeki kwamathumbu ebantwaneni

Kwizigulane zabantwana, uvavanyo lwe-calprotectin lubaluleke kakhulu. Lunokunceda ukwahlula iintlungu zesisu ezisebenzayo kwisifo sokwenyani samathumbu, kuthintelwe uvavanyo olungafunekiyo.

4) Iziphumo zovavanyo mazitolikwe njani? Zithetha ukuthini ezi xabiso?

Xa ufumana ingxelo yovavanyo, ungabona uthotho lwamanani. Athetha ukuthini?

5) Ngubani ocetyiswayo ukuba adlule kwii-calprotectin uvavanyo?

Ukuba wena okanye ilungu losapho lwakho nihlangabezana nezi zinto zilandelayo, kuyacetyiswa ukuba nidibane nogqirha malunga nokuba ngaba uvavanyo luyimfuneko na:

• Intlungu yesisu okanye isifo sohudo esingaphucukiyo kangangeeveki ezingaphezu kwezi-4
• Indle ene-mucus okanye i-pus kunye negazi
• Ukwehla kobunzima obungachazekiyo okanye i-anemia
• Sele uxilongiwe ukuba une-IBD kwaye ufuna ukubekwa esweni kwesifo
• Abantwana abaneentlungu zesisu eziphindaphindayo okanye ukukhula okulibazisekayo, ukuze kuthintelwe izifo eziphilayo
• Uvavanyo oluncedisayo kumaqela asemngciphekweni ophezulu womhlaza we-colorectal