Sezvo vakuru vezvehutano pasi rose vachikurudzira kuti pave nekuongororwa kweHIV nekukurumidza, vagadziri vekuongorora vari kukurumidza kuvandudza mapuratifomu ekuyedza ane antigen ep24, uye bvunzo dzechizvarwa chechina dzava kusvika pakukura kwekutengeserana mumisika yakasiyana-siyana.

P24 antigen, puroteni ye capsid inoonekwa nehutachiona, inowanzoonekwa mazuva gumi kusvika gumi nemana mushure mekutapukirwa neHIV - mazuva mashoma ma antibodies asati abuda. Izvi zvakaita kuti p24 ive chinhu chakakosha pakuongorora HIV muchizvarwa chechina, izvo zvinoona p24 antigen neHIV antibodies panguva imwe chete kuti zviite kuti nguva yekuongororwa ipfupike.

Kukurumidza Kwekutengeserana

PaWHX Labs Bangkok 2026, kambani yekuChina inogadzira chirwere cheHIV inonzi Wondfo yakapa bvunzo yayo yeHIV yechizvarwa chechina kuMutungamiriri weThailand Anutin Charnvirakul, ichiratidza kugona kwemuongorori uyu kuona hutachiona vhiki imwe chete isati yasvika bvunzo dzeantibody chete. Kambani iyi yakashuma kuti ine 100% sensitivity uye 99.71% chaiyo yeongororo yeHIV-1/2 antibody nep24 antigen.

MuUnited States, mvumo yemutemo yakaramba ichienderera mberi. FDA yakakwanisa kuwana mapuratifomu akawanda ekuona p24 muna 2026, anosanganisira DiaSorin's LIAISON MUREX HIV Ab/Ag HT uye Abbott's HIV Combo Next assay yepuratifomu yeAlinity i. Ose ari maviri anomiririra chemiluminescent immunoassays anokwanisa kuona panguva imwe chete HIV p24 antigen pamwe chete nema antibodies eHIV-1 neHIV-2.

Chiitiko chakakosha chehutano hwevanhu chakaitika muna Chikumi 2026, apo Seychelles neEritrea vakatora Abbott's Determine Antenatal Care Panel — bvunzo yekutanga yekukurumidza yakaongororwa neWHO inobatanidza kuonekwa kweHIV kwechizvarwa chechina ne syphilis ne hepatitis B kuongororwa kubva pamuenzaniso mumwe chete wekubata chigunwe.

Miganhu Yekutsvagisa

Kunze kwekuongororwa kwezvekutengeserana, vaongorori vedzidzo vari kutsvaga nzira yekuona p24 inonzwa zvakanyanya kuburikidza nemapuratifomu akavakirwa pa microfluidic uye nanomaterial. Chikwata cheTsinghua University munguva pfupi yapfuura chakashuma kuti microfluidic fluorescence biosensor yakawana muganho wekuona p24 we18.48 pg/mL, vachishandisa nzira dzekuwedzera signal dzisina enzyme. Pamwe chete, vaongorori vakaratidza cascaded chemiluminescence microfluidic system ine antibody orientation uye gold nanoparticle-mediated signal enhancement, vachinanga maapplication e point-of-care munzvimbo dzisina zviwanikwa zvakawanda.

Kufunga Nezvekurapa

Pasinei nekufambira mberi, matambudziko achiripo. Ongororo yakaitwa muna 2026 yakaongorora bvunzo yeVIDAS DUO AG/AB yebioMérieux yakaitwa neVIDAS DUO AG/AB yakatorwa neyakaitangira yakawana mwero wakakwira wezviratidzo zve p24 antigen zvisingazivikanwe panguva yekupatsanurwa kwehutachiona, zvichiratidza kuoma kwekuongororwa kwekutanga. Pamusoro pezvo, tsvakiridzo yazvino yakaratidza kuti p24 antigen yaingoonekwa chete mushure mekupatsanurwa kwe immune complexes musampuli dzine huwandu hwehutachiona hunopfuura 10⁴ copies/mL, zvichiratidza kuti immune complexes dzinotenderera dzinogona kuvharidzira kuonekwa kweantigen mune dzimwe nguva.

WHO inochengetedza zvinodiwa pakuongorora HIV, ichida 100% sensitivity ye enzyme immunoassays yekuona anti-HIV-1/2 uye HIV-1 p24 antigen, ine specific iri pa98% kana kupfuura.

Vagadziri vachivandudza mapuratifomu echizvarwa chechina uye vaongorori vachidzikisa miganho yekuona utachiona, kuongororwa kwep24 antigen kwagadzirira kuramba kuri pakati pezvirongwa zvepasi rose zvekuziva hutachiona hweHIV hwakakomba uye kukanganisa nzira dzekutapurirana.

Isu Baysen Medical tinogona kupaKiti yekuyedza HIV/P24 nekukurumidzanebvunzo yemhando yepamusoro uye yehuwandu. Tinokugamuchirai kuti mutibate kana muchida.