Ha balaoli ba bophelo bo botle ba lefats'e ba ntse ba phehella tlhahlobo ea HIV pele ho nako, bahlahisi ba tlhahlobo ba ntse ba potlakisa nts'etsopele ea liforomo tsa liteko tse thehiloeng ho antigen ea p24, 'me liteko tsa moloko oa bone joale li fihlile khōlong ea khoebo mebarakeng e mengata.

Antigen ea p24, protheine ea capsid ea vaerase, hangata e bonoa matsatsi a 10 ho isa ho a 14 kamora tšoaetso ea HIV - matsatsi pele li-antibodies li hlaha. Molemo ona oa baeloji o entse hore p24 e be lejoe la motheo la maano a tlhahlobo ea HIV a moloko oa bone, a lemohang antigen ea p24 le li-antibodies tsa HIV ka nako e le 'ngoe ho fokotsa nako ea tlhahlobo.

Motlakase oa Khoebo

Ho WHX Labs Bangkok 2026, moetsi oa tlhahlobo ea Chaena Wondfo o hlahisitse teko ea hae ea HIV ea moloko oa bone ho Tonakholo ea Thailand Anutin Charnvirakul, a totobatsa bokhoni ba tlhahlobo ea ho lemoha tšoaetso hoo e ka bang beke pele ho liteko tsa antibody feela. Khamphani e tlalehile kutloisiso ea 100% le ho totobala ha 99.71% bakeng sa tlhahlobo e kopaneng ea antibody ea HIV-1/2 le antigen ea p24.

United States, ditumello tsa taolo di ntse di tsamaisana le maemo. FDA e se e amohetse di-platform tse ngata tsa ho lemoha p24 ka 2026, ho kenyeletswa DiaSorin's LIAISON MUREX HIV Ab/Ag HT le teko ya Abbott's HIV Combo Next bakeng sa sethala sa Alinity i. Ka bobedi di emela diteko tsa chemiluminescent immunoassays tse kgonang ho lemoha antigen ya HIV p24 ka nako e le nngwe hammoho le di-antibodies ho HIV-1 le HIV-2.

Ketsahalo ea bohlokoa bophelong bo botle ba sechaba e etsahetse ka Phuptjane 2026, ha Seychelles le Eritrea li amohela Abbott's Determine Antenatal Care Panel - teko ea pele e potlakileng e khethiloeng ke WHO e kopanyang ho fumanoa ha HIV molokong oa bone le syphilis le tlhahlobo ea hepatitis B ho tsoa sampole e le 'ngoe ea monoana.

Meeli ea Lipatlisiso

Ka ntle ho tlhahlobo ea khoebo, bafuputsi ba thuto ba ntse ba phehella ho lemoha p24 ka mokhoa o bobebe ka li-platform tse thehiloeng ho microfluidic le nanomaterial. Sehlopha se tsoang Univesithing ea Tsinghua se sa tsoa tlaleha hore microfluidic fluorescence biosensor e fihletse moeli oa ho lemoha oa 18.48 pg/mL bakeng sa p24, se sebelisa maano a ho eketsa lets'oao ntle le enzyme. Ka thoko, bafuputsi ba bontšitse sistimi ea microfluidic ea chemiluminescence e arotsoeng ka sekhahla e nang le tataiso ea li-antibody le ntlafatso ea lets'oao e tsamaisoang ke nanoparticle ea khauta, e shebaneng le lits'ebetso tsa tlhokomelo libakeng tse fokolang tsa mehloli.

Mehopolo ea Bongaka

Ho sa tsotellehe tsoelo-pele, liphephetso li ntse li tsoela pele. Phuputso ea 2026 e neng e hlahloba tlhahlobo ea bioMérieux ea VIDAS DUO AG/AB khahlanong le ea pele ho eona e fumane sekhahla se phahameng sa matšoao a antigen a p24 a sa tsejoeng nakong ea karohano e matla ea tšoaetso, e totobatsang ho rarahana ha tlhahlobo ea pele. Ho feta moo, lipatlisiso tsa morao tjena li bontšitse hore antigen ea p24 e ne e ka bonoa feela ka mor'a ho arola metsoako ea 'mele ea ho itšireletsa mafung lisampoleng tse nang le meroalo ea vaerase e fetang likopi tse 10⁴/mL, e leng se bontšang hore metsoako ea 'mele ea ho itšireletsa mafung e potolohang e ka pata ho fumanoa ha antigen maemong a mang.

WHO e boloka litekanyetso tsa ts'ebetso bakeng sa ho fumana tlhahlobo ea HIV, e hlokang kutloisiso ea 100% bakeng sa liteko tsa immunoassay tsa enzyme tse lemohang anti-HIV-1/2 le HIV-1 p24 antigen, ka ho khetheha ho 98% kapa ho feta.

Ha bahlahisi ba ntse ba ntlafatsa liforomo tsa moloko oa bone 'me bafuputsi ba fokotsa meeli ea ho lemoha, tlhahlobo e thehiloeng ho antigen ea p24 e ikemiselitse ho lula e le ea bohlokoa maanong a lefats'e a ho khetholla tšoaetso e matla ea HIV le ho sitisa liketane tsa phetisetso.

Re ka fana ka Baysen MedicalKiti ea tlhahlobo ea HIV/P24 e potlakilengka teko ea boleng le ea bongata. Rea u amohela ho ikopanya le rona haeba u na le tlhoko.